Understanding how the immune system protects against respiratory viruses.
Official title: Mechanisms of Immune Protection Against Respiratory Viruses
Funded at Washington University · NIH-10824574 · Data updated 2026-11-12
This study is looking at how vaccines help our immune system fight off respiratory viruses and how long that protection lasts, and it's for people who want to understand more about how their bodies respond to vaccines and infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 4, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $2,380,350 |
| NIH project number | 1U19AI181103-01 |
| Project ID | NIH-10824574 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are adults aged 21 and older who are interested in contributing to vaccine research and have not previously been vaccinated against the targeted respiratory viruses.
✕Less likely to help
Patients who are under 21 years old or those with compromised immune systems may not benefit from this research.
What this research studies
This research investigates the immune responses to respiratory viruses, particularly focusing on how vaccines can generate long-lasting protection. It aims to define the mechanisms that allow the immune system to maintain effective responses after vaccination, including the role of specific immune cells like B cells and T cells. The study will involve human participants to assess how well their immune systems respond to vaccines and infections, providing insights that could lead to improved vaccine designs.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective vaccines that provide long-lasting immunity against respiratory viruses.
How similar studies have gone: Previous research has shown promising results in understanding immune responses to vaccines, indicating that this approach has the potential for significant advancements.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Ellebedy, Ali Hassan — Washington University
- Study coordinator: Ellebedy, Ali Hassan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.