Understanding how the immune system interacts with gut bacteria
Immune Interactions with the Mucus-Associated Microbiota
This study is looking at how the immune system interacts with the good bacteria in the gut for people with inflammatory bowel disease (IBD), hoping to find new ways to help manage inflammation and improve treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10879110 on NIH RePORTER |
What this research studies
This research investigates how the immune system responds to the bacteria that naturally live in the gut, particularly in individuals with inflammatory bowel disease (IBD). It aims to uncover the mechanisms that help the body tolerate these normally harmless bacteria, which can sometimes trigger inflammation. By studying immune responses, especially the role of specific antibodies, the research seeks to identify ways to prevent or treat intestinal inflammation. Patients may benefit from insights that could lead to new therapies for managing IBD.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are diagnosed with inflammatory bowel disease.
Not a fit: Patients without inflammatory bowel disease or those under 21 years old may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from inflammatory bowel disease.
How similar studies have performed: Previous research has shown promising results in understanding immune interactions with gut microbiota, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Maynard, Craig L — University of Alabama at Birmingham
- Study coordinator: Maynard, Craig L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.