Understanding how the immune system affects Candida albicans in the gut
Dissecting the impact of immune environment on Candida albicans pathogenic potential in the gut
This study is looking at how your immune system affects the way a common fungus called Candida albicans can cause problems in your gut, and it aims to help us understand how to keep your gut healthy and prevent infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11047962 on NIH RePORTER |
What this research studies
This research investigates how different immune environments influence the ability of the fungus Candida albicans to cause disease in the gut. By examining the role of immune factors, particularly IgA antibodies, the study aims to uncover how these immune responses can alter the pathogenic potential of C. albicans. The research will involve both laboratory experiments and analysis of immune responses in the gut, providing insights into how the immune system interacts with this common fungus. This could lead to a better understanding of gut health and infections related to C. albicans.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with immune deficiencies or those experiencing gastrointestinal issues related to fungal infections.
Not a fit: Patients without any immune system concerns or those not affected by Candida albicans infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating infections caused by Candida albicans in patients with compromised immune systems.
How similar studies have performed: Previous research has shown that understanding the immune response to pathogens can lead to significant advancements in treatment, suggesting that this approach may yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Ost, Kyla — University of Colorado Denver
- Study coordinator: Ost, Kyla
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.