Understanding how the heart matures from fetal stages to adulthood
Locking and Unlocking Cardiac Maturation
['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-11033038
This study is looking at how the heart grows and develops from late pregnancy into adulthood, with the goal of finding new ways to treat heart diseases and improve heart cell healing, which could help patients with heart problems.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11033038 on ClinicalTrials.gov |
What this research studies
This research investigates the processes involved in the maturation of the heart from late fetal stages into adulthood. It focuses on understanding the genetic and regulatory mechanisms that influence cardiac development and how these processes can lead to heart diseases. By studying specific transcription factors and their roles in cardiac maturation, the research aims to uncover new therapeutic strategies for heart failure and improve heart cell regeneration. Patients may benefit from insights that could lead to innovative treatments for congenital heart conditions and other cardiac disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old with abnormal heart development or congenital heart conditions.
Not a fit: Patients with fully developed hearts and no history of cardiac abnormalities may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for heart diseases and improved outcomes for patients with congenital heart abnormalities.
How similar studies have performed: Previous research has shown promise in understanding cardiac development and maturation, suggesting that this approach could yield significant advancements in treatment.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KELLY, DANIEL PATRICK — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: KELLY, DANIEL PATRICK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiac Diseases, Cardiac Disorders