Understanding how the fungus Coccidioides becomes harmful to humans
Fungal Virulence: Identifying the factors that control virulence and the growth in parasitic form of Coccidioides
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11004694
This study is looking at a type of fungus that can make people sick, and it's trying to understand how it grows and changes in the environment so it can infect us, which could help find better ways to fight it off.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11004694 on ClinicalTrials.gov |
What this research studies
This research investigates the Coccidioides species, which can cause serious infections in humans. The team will study how these fungi grow in the environment and transform into a form that can infect people. By examining the genes and proteins involved in this process, they aim to uncover how the fungus evades the immune system. This research employs advanced techniques like transcriptomics and proteomics to identify key factors that contribute to the fungus's virulence and its ability to thrive in the human body.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of Coccidioides infections, particularly those living in endemic areas.
Not a fit: Patients who are not at risk for Coccidioides infections or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments and preventive measures for infections caused by Coccidioides.
How similar studies have performed: Previous research has shown promise in understanding fungal virulence, but this specific approach to studying Coccidioides is relatively novel.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEYHAN, SINEM — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: BEYHAN, SINEM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Candidate Disease Gene