Understanding how the environment affects endometriosis lesions

Parsing the Interplay Between Biophysical and Biochemical Microenvironment Cues On Endometriosis Lesion Phenotypes Using Microphysiological Systems

['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11115568

This study is exploring how the surroundings of endometriosis lesions affect symptoms and treatment responses, with the hope of creating better, personalized treatment options for patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded)
Locations1 site (CAMBRIDGE, UNITED STATES)
Trial IDNIH-11115568 on ClinicalTrials.gov

What this research studies

This research investigates the complex interactions between the physical and chemical environments surrounding endometriosis lesions. By using advanced models that mimic human tissue, the study aims to identify different biological mechanisms that may contribute to the varied symptoms and responses to treatment in endometriosis patients. The goal is to create a new framework for classifying patients based on these mechanisms, which could lead to more personalized and effective treatment strategies. Patients will be involved in developing and testing these innovative models to better understand their condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with endometriosis, particularly those experiencing symptoms at a younger age.

Not a fit: Patients who do not have endometriosis or those who are significantly older than the typical age of onset may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more tailored treatments for endometriosis, improving outcomes for patients.

How similar studies have performed: Other research has shown promise in using innovative models to study complex diseases, suggesting that this approach could yield valuable insights.

Where this research is happening

CAMBRIDGE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.