Understanding how the cytoskeleton affects neurodegeneration
INVESTIGATING THE ROLE OF THE CYTOSKELETON IN NEURODEGENERATION
This study is looking at how changes in the cell's structure might affect the buildup of harmful proteins in the brains of people with Alzheimer's, with the hope of finding new ways to help keep brain cells healthy and improve treatment options.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10874593 on NIH RePORTER |
What this research studies
This research investigates the role of the cytoskeleton in the progression of neurodegenerative diseases, particularly Alzheimer's Disease. It aims to understand how disruptions in the cytoskeletal dynamics contribute to the accumulation of toxic proteins in the brain, which are linked to neuronal dysfunction. By exploring the mechanisms of the autophagy-lysosomal network, the study seeks to identify potential therapeutic strategies to enhance protein disposal and protect neuronal health. Patients may benefit from insights that could lead to new treatments targeting these cellular processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are diagnosed with Alzheimer's Disease or related neurodegenerative disorders.
Not a fit: Patients with neurodegenerative diseases not related to protein aggregation or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's Disease and other neurodegenerative conditions.
How similar studies have performed: Previous research has shown promising results in understanding the role of cytoskeletal dynamics in neurodegeneration, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Stephens, Morgan Catherine — Baylor College of Medicine
- Study coordinator: Stephens, Morgan Catherine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.