Understanding how the Coccidioides fungus interacts with the human immune system
Molecules and Pathways at the Coccidioides Host-Pathogen Interface
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11004121
This study is looking at how the Coccidioides fungus interacts with our immune system to help find better ways to diagnose and treat people who are dealing with chronic infections, especially those in California.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11004121 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between the Coccidioides fungus and the human immune system, focusing on identifying specific molecules and pathways involved in this relationship. By utilizing models such as macrophages and mice, as well as clinical samples from patients in California, the research aims to uncover factors that contribute to chronic and disseminated infections. The study also seeks to evaluate the potential of Coccidioides antigens and host biomarkers for improving diagnosis and treatment outcomes for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with coccidioidomycosis or those experiencing chronic fungal infections.
Not a fit: Patients with fungal infections not related to Coccidioides or those without any fungal infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted therapies for coccidioidomycosis, enhancing patient care.
How similar studies have performed: Previous research has shown promise in understanding host-pathogen interactions in fungal infections, suggesting that this approach could yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIL, ANITA — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: SIL, ANITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.