Understanding how the cerebellum influences emotions and behavior
Multi-level dissection of cerebello-limbic connectivity
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11013838
This study is looking at how a part of the brain called the cerebellum helps control our emotions and behaviors, especially when it comes to learning and remembering things, and it’s aimed at helping people with autism spectrum disorders understand their feelings better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11013838 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the cerebellum in regulating emotional responses and behaviors, particularly in the context of learning and memory. By examining the connections between the cerebellum and key brain areas involved in emotion, such as the amygdala, the researchers aim to uncover how these circuits function and contribute to behaviors like fear extinction. The study employs advanced techniques like circuit tracing and single-cell sequencing to analyze the properties of specific cell types within these circuits. This research could provide insights into the biological mechanisms underlying emotional and behavioral disorders, particularly in individuals with autism spectrum disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorders who experience challenges related to emotional regulation and learning.
Not a fit: Patients without autism spectrum disorders or those not experiencing emotional or behavioral challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing emotional and behavioral challenges in patients, especially those with autism spectrum disorders.
How similar studies have performed: Previous research has shown promising results in understanding cerebellar functions related to behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FIORAVANTE, DIASYNOU — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: FIORAVANTE, DIASYNOU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder