Understanding how the cerebellum controls movement.
Control of movements by the cerebellum
This study looks at how a part of the brain called the cerebellum helps people with movement problems caused by cerebellar diseases, focusing on special brain cells that help correct mistakes in movement.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11037940 on NIH RePORTER |
What this research studies
This research investigates how the cerebellum, a part of the brain, helps control and adjust movements, especially in individuals with cerebellar diseases. It focuses on how specific brain cells, called Purkinje cells, communicate and respond to errors during movement. By studying these cells and their interactions, the research aims to decode the mechanisms that allow for precise movement control, which can be disrupted in various disorders. The approach involves advanced techniques to analyze the firing patterns of these cells and their role in movement correction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cerebellar diseases or disorders that affect movement coordination.
Not a fit: Patients with conditions unrelated to cerebellar function or those without movement disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with cerebellar disorders, enhancing their ability to perform everyday movements.
How similar studies have performed: Previous research has shown promising results in understanding cerebellar function and its role in movement control, suggesting that this approach could yield significant insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Shadmehr, Reza — Johns Hopkins University
- Study coordinator: Shadmehr, Reza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.