Understanding how the cerebellum controls movement.
Official title: Control of movements by the cerebellum
Funded at Johns Hopkins University · NIH-11037940 · Data updated 2026-11-12
This study looks at how a part of the brain called the cerebellum helps people with movement problems caused by cerebellar diseases, focusing on special brain cells that help correct mistakes in movement.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 15, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $648,102 |
| NIH project number | 5R37NS128416-03 |
| Project ID | NIH-11037940 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cerebellar diseases or disorders that affect movement coordination.
✕Less likely to help
Patients with conditions unrelated to cerebellar function or those without movement disorders may not benefit from this research.
What this research studies
This research investigates how the cerebellum, a part of the brain, helps control and adjust movements, especially in individuals with cerebellar diseases. It focuses on how specific brain cells, called Purkinje cells, communicate and respond to errors during movement. By studying these cells and their interactions, the research aims to decode the mechanisms that allow for precise movement control, which can be disrupted in various disorders. The approach involves advanced techniques to analyze the firing patterns of these cells and their role in movement correction.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with cerebellar disorders, enhancing their ability to perform everyday movements.
How similar studies have gone: Previous research has shown promising results in understanding cerebellar function and its role in movement control, suggesting that this approach could yield significant insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Shadmehr, Reza — Johns Hopkins University
- Study coordinator: Shadmehr, Reza
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.