Understanding how the cerebellum affects speech production
The role of the cerebellum in speech
This study looks at how problems with a part of the brain called the cerebellum can affect how clearly and naturally people with cerebellar ataxia speak, and it hopes to find ways to help improve their speech.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11133867 on NIH RePORTER |
What this research studies
This research investigates the role of the cerebellum in speech production, particularly focusing on how damage to this brain region affects speech intelligibility and naturalness in individuals with cerebellar ataxia. The study aims to uncover the mechanisms by which the cerebellum contributes to the neural control of speech, including how it generates sensory predictions and updates them based on feedback. By exploring these processes, the research seeks to identify potential evidence-based treatments for speech impairments caused by cerebellar dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cerebellar ataxia who experience speech motor impairments.
Not a fit: Patients without cerebellar dysfunction or those who do not have speech production issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve speech production for individuals with cerebellar ataxia.
How similar studies have performed: While the specific mechanisms of cerebellar influence on speech are not fully understood, related research has shown promise in understanding brain functions and developing targeted therapies.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Houde, John Francis — University of California, San Francisco
- Study coordinator: Houde, John Francis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.