Understanding how the cerebellum affects cognitive sequencing
Investigation of cerebellar involvement in cognitive sequencing
This study is looking at how a part of the brain called the cerebellum helps with thinking and remembering things in order, which is important for tasks like learning new words, and it's specifically for people with coordination issues due to cerebellar ataxia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10892200 on NIH RePORTER |
What this research studies
This research investigates the role of the cerebellum in cognitive processes, particularly how it helps in sequencing information, which is crucial for tasks like verbal working memory and language acquisition. The study will utilize advanced imaging techniques, such as fMRI, to explore brain activity and connectivity in patients with cerebellar ataxia, a condition characterized by coordination impairments. By examining how these patients perform on tasks that require sequencing, the research aims to uncover the neural mechanisms underlying cognitive functions linked to the cerebellum.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cerebellar ataxia who experience cognitive sequencing difficulties.
Not a fit: Patients without cerebellar ataxia or those who do not exhibit cognitive sequencing challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for cognitive impairments associated with cerebellar dysfunction.
How similar studies have performed: Previous studies have shown promising results in understanding the cerebellum's role in cognition, but this specific approach is relatively novel.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Desmond, John E — Johns Hopkins University
- Study coordinator: Desmond, John E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.