Understanding how the cell nucleus works in health and disease
Official title: Molecular mechanisms in the mammalian cell nucleus
Funded at Rice University · NIH-10940774 · Data updated 2026-11-12
This study is looking at how the tiny parts inside our cells work, especially in the nucleus, to better understand diseases like cancer and genetic disorders, which could help develop new treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $344,031 |
| NIH project number | 1R35GM155365-01 |
| Project ID | NIH-10940774 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions such as cancers, laminopathies, or ciliopathies that involve cellular and nuclear dysfunction.
✕Less likely to help
Patients with unrelated health conditions or those not experiencing cellular dysfunction may not benefit from this research.
What this research studies
This research focuses on exploring the intricate structures and functions of the mammalian cell nucleus using advanced imaging techniques. By employing innovative tools and algorithms, the team aims to uncover the molecular mechanisms that govern cellular behavior and contribute to diseases such as cancer and genetic disorders. Patients may benefit from insights gained about how cellular processes are altered in various conditions, potentially leading to new therapeutic strategies. The research involves detailed analysis of chromatin dynamics and gene regulation in both healthy and diseased cells.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating diseases related to cellular dysfunction.
How similar studies have gone: Previous research using advanced imaging techniques has shown promise in elucidating cellular mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rice University
Houston, United States Active
Researchers
- Principal investigator: Gustavsson, Anna Karin Eva — Rice University
- Study coordinator: Gustavsson, Anna Karin Eva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.