NIH-funded research Career grant

Understanding how the brain translates vision into movement

Official title: Molecular determinants of synaptic specificity underlying a visuomotor transformation

Funded at University of California Los Angeles · NIH-10864704 · Data updated 2026-11-12

This study looks at how the brain helps us turn what we see into movements, using fruit flies to understand the genes and connections involved, which could help us learn more about problems with vision and movement in people with certain neurological conditions.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startJuly 1, 2024
Project endJune 30, 2026
Funding year2024
Award (this year)$109,878
NIH project number1K99EY036123-01
Project IDNIH-10864704 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with neurological disorders that impair visuomotor processing.

Less likely to help

Patients with conditions unrelated to visuomotor processing or those who do not have neurological disorders may not benefit from this research.

What this research studies

This research investigates the molecular and developmental factors that enable the brain to convert visual information into motor actions, focusing on a model organism called Drosophila. By examining the synaptic connections between sensory and motor neurons, the study aims to uncover the genetic and molecular mechanisms that underlie this critical process. The approach integrates advanced techniques such as transcriptomics and connectomics to link specific genes to the structure and function of neural circuits. This research could provide insights into the causes of impaired visuomotor processing seen in various neurological disorders.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating neurological disorders that affect movement and vision.

How similar studies have gone: Other research has shown success in using model organisms to understand complex neural processes, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Dombrovskiy, Mark — University of California Los Angeles
  • Study coordinator: Dombrovskiy, Mark

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.