Understanding how the brain suppresses distracting touch sensations

The Neural Basis of Active Sensory Gain Suppression in the Somatosensory System

NIH-funded research University of Rochester · NIH-10994042

This study is looking at how our brains focus on important touch sensations while tuning out distractions, and it aims to help people with conditions like ADHD and autism better understand their sensory experiences.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10994042 on NIH RePORTER

What this research studies

This research investigates the neural mechanisms that allow the brain to focus on important tactile information while ignoring distractions. By using advanced techniques like optogenetics and electrophysiology, the study aims to explore how attention influences sensory processing in the brain's neocortex. The research will involve both human and non-human primate models to gain insights into the dynamics of sensory gain suppression. Patients may benefit from a better understanding of sensory processing disorders, such as ADHD and autism, which can affect attention and perception.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with sensory processing disorders, such as ADHD or autism.

Not a fit: Patients without sensory processing issues or those not affected by attention-related disorders may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for sensory processing disorders, enhancing patients' quality of life.

How similar studies have performed: Previous research has shown promising results in understanding sensory processing and attention mechanisms, indicating that this approach could yield valuable insights.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorderAutistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.