NIH-funded research R01 grant

Understanding how the brain represents the meanings of words

Official title: Neural Representation of Lexical Concepts

Funded at Medical College of Wisconsin · NIH-11039930 · Data updated 2026-11-12

This study is looking at how the brain understands the meanings of words, especially for people with language challenges like aphasia, to help create better treatments for those who have trouble with language.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin
NIH-funded
Lab location1 site (Milwaukee, United States)
Project startApril 1, 2024
Project endMarch 31, 2029
Funding year2025
Award (this year)$403,014
NIH project number5R01DC020932-02
Project IDNIH-11039930 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with acquired language disorders, particularly those experiencing aphasia.

Less likely to help

Patients without language impairments or those with developmental language disorders may not benefit from this research.

What this research studies

This research investigates how the brain encodes the meanings of words, particularly for individuals with acquired language disorders like aphasia. By examining different patterns of semantic impairments, the study aims to identify how various features of experience, such as perception and emotion, contribute to word meaning. The researchers will develop a model based on human ratings of these features to better understand the neural activity associated with specific words. This could lead to improved interventions for patients struggling with language processing.

Why it matters

Potential benefit: If successful, this research could enhance treatment strategies for individuals with language disorders, improving their communication abilities.

How similar studies have gone: Previous research has shown promising results in understanding semantic processing in the brain, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Medical College of Wisconsin
    Milwaukee, United States
    Active

Researchers

  • Principal investigator: Fernandino, Leonardo F — Medical College of Wisconsin
  • Study coordinator: Fernandino, Leonardo F

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.