NIH-funded research Career grant

Understanding how the brain remembers social interactions

Official title: Investigating the neural mechanisms of social memory in the hippocampal-cortical network

Funded at Columbia University Health Sciences · NIH-11000846 · Data updated 2026-11-12

This study is looking at how our brains remember social interactions, which is really important for people with conditions like autism and schizophrenia, to help us understand their social behavior better.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startDecember 15, 2023
Project endNovember 30, 2025
Funding year2025
Award (this year)$123,715
NIH project number5K99MH135166-02
Project IDNIH-11000846 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with autism spectrum disorder or schizophrenia who experience challenges with social memory and cognition.

Less likely to help

Patients without any psychiatric disorders or those who do not experience social cognition deficits may not benefit from this research.

What this research studies

This research investigates the neural mechanisms behind social memory, which is crucial for understanding social behavior in individuals with psychiatric disorders like autism and schizophrenia. By examining the hippocampal-cortical network, the study aims to uncover how the brain processes familiarity and recollection during social interactions. The approach involves using artificial neural networks and neural recordings from both mice and human subjects exposed to social stimuli, allowing for a comprehensive analysis of social cognition. The findings could provide insights into the underlying neural processes that contribute to social memory.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for social cognition deficits in psychiatric disorders.

How similar studies have gone: Previous research has shown promising results in understanding social cognition through neural mechanisms, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Posani, Lorenzo — Columbia University Health Sciences
  • Study coordinator: Posani, Lorenzo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.