Understanding how the brain regulates social interactions for better mental health
Establishing Neural Control Systems for Social Homeostasis
This study is looking at how our brains help us balance socializing and being alone, especially for people with autism, to understand how these interactions can improve our mental and physical health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11082400 on NIH RePORTER |
What this research studies
This research investigates the neural mechanisms that control social interactions and their impact on mental and physical health. By exploring the concept of 'social homeostasis', the study aims to identify the brain circuits involved in balancing social contact and isolation. Using advanced techniques like 2-photon microscopy, researchers will analyze how these neural systems function, particularly in individuals with autism spectrum disorder who often experience social disruptions. The goal is to provide insights into how social interactions can be optimized for better health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older, particularly those with autism spectrum disorder or related affective disorders.
Not a fit: Patients who do not have any social interaction difficulties or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving mental health by enhancing social interactions.
How similar studies have performed: While the concept of social homeostasis is relatively novel, previous research has successfully identified neural control systems for other essential resources, suggesting potential for success in this area.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Mchenry, Jenna Ann — Duke University
- Study coordinator: Mchenry, Jenna Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.