Understanding how the brain regulates sleep after being awake for too long
Neural Correlates of Sleep Homeostasis
This study is looking at how certain brain cells make us feel sleepier when we've been awake for a long time, which is something many of us deal with in our busy lives, and it hopes to find ways to help us cope better with not getting enough sleep.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston VA Research Institute, INC. NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11067869 on NIH RePORTER |
What this research studies
This research investigates the brain mechanisms that lead to increased sleepiness after prolonged periods of wakefulness, a condition many people experience due to busy lifestyles. The study focuses on specific neurons in the basal forebrain that may play a crucial role in this sleep response. By examining how these neurons interact with other brain systems, the research aims to uncover the underlying processes that contribute to sleep regulation. This knowledge could help develop strategies to mitigate the negative effects of sleep deprivation on cognition and behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who frequently experience sleep deprivation due to work or lifestyle demands.
Not a fit: Patients with chronic sleep disorders unrelated to sleep deprivation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for sleep-related issues and improve overall cognitive function in individuals suffering from sleep deprivation.
How similar studies have performed: Previous research has shown promising results in understanding sleep mechanisms, but this specific approach focusing on basal forebrain neurons is relatively novel.
Where this research is happening
Boston, United States
- Boston VA Research Institute, INC. — Boston, United States (Active)
Researchers
- Principal investigator: Basheer, Radhika — Boston VA Research Institute, INC.
- Study coordinator: Basheer, Radhika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.