Understanding how the brain regulates goal-directed behavior
Prefrontal CRF and the Regulation of Goal Directed Behavior
This study is looking at how a part of the brain called the prefrontal cortex helps with thinking and staying focused, especially in people with ADHD, to find new ways to improve their attention and memory.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10995287 on NIH RePORTER |
What this research studies
This research investigates the role of the prefrontal cortex in managing cognitive processes that guide goal-directed behavior. It focuses on how dysregulation in this area can lead to behavioral disorders, particularly in conditions like ADHD. By studying the effects of corticotropin-releasing factor (CRF) on cognitive functions such as working memory and sustained attention, the research aims to uncover new treatment avenues. The approach includes both animal models and advanced neurobiological techniques to explore the underlying mechanisms of cognitive dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing cognitive dysfunction related to behavioral disorders, particularly those with ADHD.
Not a fit: Patients with cognitive dysfunction not related to behavioral disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cognitive dysfunction associated with behavioral disorders.
How similar studies have performed: Previous research has shown promise in understanding the neurobiology of cognitive processes, suggesting that this approach could yield significant insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Berridge, Craig W — University of Wisconsin-Madison
- Study coordinator: Berridge, Craig W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.