Understanding how the brain regulates blood sugar levels
Official title: Neural mechanisms regulating glucose homeostasis
Funded at University of Rochester · NIH-11173762 · Data updated 2026-11-12
This study is looking at how certain brain cells might help control blood sugar levels, which could lead to new ways to manage type 2 diabetes and improve treatment options for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 2, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $546,522 |
| NIH project number | 5R01DK135621-03 |
| Project ID | NIH-11173762 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with type 2 diabetes who are interested in understanding new treatment approaches.
✕Less likely to help
Patients without type 2 diabetes or those with other forms of diabetes may not benefit from this research.
What this research studies
This research investigates the role of specific neurons in the brain that may influence blood sugar regulation, particularly in the context of type 2 diabetes. The study focuses on a component of the brain's renin-angiotensin system, which has been linked to metabolic processes. By examining how these neurons interact with glucose levels, the research aims to uncover new mechanisms that could lead to better management of diabetes. Patients may benefit from insights that could inform future treatments or interventions for blood sugar control.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing blood sugar levels in patients with type 2 diabetes.
How similar studies have gone: Other research has shown promising results in understanding the brain's role in metabolic regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Feng Earley, Yumei — University of Rochester
- Study coordinator: Feng Earley, Yumei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.