Understanding how the brain processes sound after hearing loss
Cellular Mechanisms of Auditory Information Processing
['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10860929
This study looks at how hearing loss affects the way our brains process sounds, especially as we age or are exposed to loud noises, and it aims to understand how these changes can impact our ability to communicate and think clearly.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-10860929 on ClinicalTrials.gov |
What this research studies
This research investigates the cellular mechanisms involved in auditory information processing, particularly focusing on how hearing loss affects the brain's ability to interpret sound. It examines changes in the cochlea and auditory nerve pathways that occur due to factors like aging, noise exposure, and certain medications. By studying these changes, the research aims to uncover how they impact communication and cognitive functions in adults. The approach includes detailed analysis of neuronal circuits and synaptic functions in the brain's auditory centers.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing hearing loss due to various causes.
Not a fit: Patients with normal hearing or those whose hearing loss is not related to the mechanisms being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for individuals experiencing hearing loss.
How similar studies have performed: Previous research has shown promising results in understanding auditory processing in animal models, but this specific focus on hearing loss in adults is relatively novel.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANIS, PAUL B — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: MANIS, PAUL B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.