Understanding how the brain processes information in bipolar disorder

Establishing Network Neuroscience Mechanisms of Efficiency of Evidence Accumulation in a Well-Characterized Sample with Bipolar Disorder: A Multi-Modal Clinical Imaging Study

NIH-funded research University of Michigan at Ann Arbor · NIH-11064023

This study is looking at how the brains of people with bipolar disorder gather information and make choices, and it will compare their brain activity to that of healthy individuals to see what differences exist.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11064023 on NIH RePORTER

What this research studies

This research investigates the brain mechanisms that affect how individuals with bipolar disorder accumulate information and make decisions. By using advanced imaging techniques and computational models, the study aims to identify how the brain's network connectivity influences this cognitive process. The research will involve comparing brain activity in adults with bipolar disorder to that of healthy adults to uncover differences in information processing. Participants will be part of a well-characterized sample from the Prechter Longitudinal Study of Bipolar Disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with bipolar disorder.

Not a fit: Patients who do not have bipolar disorder or are under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for bipolar disorder by targeting cognitive deficits.

How similar studies have performed: Previous research has shown promising results in understanding cognitive processes in psychiatric disorders using similar network neuroscience approaches.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.