Understanding how the brain processes important sounds
Dendritic Mechanisms Underlying Behaviorally-Relevant Activity in a Descending Auditory Pathway
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11221067
This study looks at how the brain helps us focus on important sounds, like speech, by examining how different parts of the brain work together in mice, and it aims to help us understand how we listen better in noisy environments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11221067 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain's auditory system processes sounds that are important for understanding speech and other complex auditory information. By studying the connections between the auditory cortex and midbrain in mice, the researchers aim to uncover how the brain prioritizes certain sounds over others during active listening. The approach involves advanced techniques to observe and analyze the neural mechanisms that contribute to this selective auditory processing, which is crucial for effective communication and learning.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related hearing loss or auditory processing difficulties.
Not a fit: Patients with normal hearing or those not experiencing age-related auditory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for age-related hearing loss and better auditory processing strategies for affected individuals.
How similar studies have performed: Previous research has shown promising results in understanding auditory processing mechanisms, but this specific approach focusing on descending pathways is relatively novel.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: APOSTOLIDES, PIERRE F — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: APOSTOLIDES, PIERRE F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.