Understanding how the brain processes flavor from taste and smell

Development of the multisensory computations underlying flavor processing

NIH-funded research Wake Forest University Health Sciences · NIH-10996146

This study looks at how our brains mix taste and smell to help us enjoy food, using awake rats to understand how this process works at a tiny level, which could help us learn more about how our eating habits affect our flavor preferences.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-10996146 on NIH RePORTER

What this research studies

This research investigates how the brain combines taste and smell to create the perception of flavor, which significantly influences food choices and health. By using awake rats as a model, the study aims to explore the neural mechanisms behind flavor processing at a cellular level, allowing for precise control over the flavor experience. The research seeks to uncover how individual eating experiences shape flavor perception, addressing gaps left by human imaging techniques.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be adults interested in understanding the neural basis of flavor perception and its impact on eating behaviors.

Not a fit: Patients who are not adults or those with conditions that severely impair taste or smell may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of flavor processing, potentially influencing dietary choices and health outcomes.

How similar studies have performed: While the approach of using animal models to study flavor processing is established, the specific methodologies and hypotheses being tested in this research may offer novel insights.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.