Understanding how the brain processes emotions and their disorders

Spatiotemporal dynamics of the human emotion network

NIH-funded research University of California, San Francisco · NIH-10850944

This study is looking at how problems in the brain's emotion system can cause feelings of anxiety and depression, and it aims to find new ways to diagnose and treat these issues by closely examining how our brains process different emotions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10850944 on NIH RePORTER

What this research studies

This research investigates the brain's emotion network, focusing on how its dysfunction can lead to symptoms like anxiety and depression. Using advanced techniques like intracranial electroencephalography (iEEG), the study aims to map the dynamics of this network with high precision. By examining how different emotions are represented in the brain, the research seeks to uncover the underlying mechanisms of affective disorders. This could lead to the identification of specific biomarkers that help in diagnosing and treating these conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who experience affective symptoms related to anxiety or depression.

Not a fit: Patients who do not experience any affective symptoms or those under 21 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted treatments for emotional disorders.

How similar studies have performed: Previous research has shown promise in understanding brain networks related to emotions, but this approach using iEEG is relatively novel.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.