Understanding how the brain processes complex sounds like music and speech

CRCNS: Online optimization for probing high-level auditory representations

NIH-funded research Johns Hopkins University · NIH-11089381

This study is exploring how the brains of marmosets react to different sounds, like animal calls and music, to help us understand how our brains process complex sounds.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11089381 on NIH RePORTER

What this research studies

This research investigates how the auditory cortex of marmosets responds to complex sounds, such as animal vocalizations and music. By using advanced techniques to record the activity of many neurons simultaneously, the researchers aim to uncover the neural coding mechanisms behind harmonic sounds. They will employ an innovative online adaptive stimulus optimization approach to design sound stimuli that effectively probe the brain's responses. This method allows for a more detailed understanding of how the brain interprets rich auditory information.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals with an interest in auditory processing or those affected by hearing impairments.

Not a fit: Patients who do not have auditory processing issues or are not interested in the mechanisms of sound perception may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of auditory processing, potentially leading to improved treatments for hearing disorders.

How similar studies have performed: Previous research has shown success in using computational models to study sensory processing, indicating that this approach has potential for significant findings.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.