Understanding how the brain processes chemical signals to influence social behavior
Official title: Inhibitory plasticity and social learning in the accessory olfactory bulb
Funded at University of Rochester · NIH-11032040 · Data updated 2026-11-12
This study is looking at how certain brain cells help us respond to social situations by processing chemical signals, and it could help us understand social behavior issues, like those seen in autism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $490,504 |
| NIH project number | 5R01DC021213-02 |
| Project ID | NIH-11032040 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with autism spectrum disorder or related social behavior challenges.
✕Less likely to help
Patients with non-social behavioral disorders or those without any neurological conditions may not benefit from this research.
What this research studies
This research investigates the neural circuitry of the accessory olfactory system, which plays a crucial role in how chemical signals affect social behavior in both humans and animal models like mice. By examining the activity of specific neurons in the accessory olfactory bulb, the study aims to uncover how these neurons adapt based on social experiences. The research employs various physiological techniques to analyze the cellular and synaptic functions of these neurons, focusing on their plasticity in response to social interactions. This understanding could lead to better insights into disorders that impact social behavior, such as autism spectrum disorder.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of social behavior mechanisms, potentially leading to improved therapies for conditions like autism spectrum disorder.
How similar studies have gone: Previous research has shown promising results in understanding the role of neural circuits in social behavior, indicating that this approach has potential for success.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Meeks, Julian P — University of Rochester
- Study coordinator: Meeks, Julian P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.