Understanding how the brain processes avoidance behavior
The role of valence encoding amygdala ensembles in avoidance behavior
['FUNDING_CAREER'] · UNIVERSITY OF WASHINGTON · NIH-11032427
This study looks at how certain brain cells in the amygdala help us decide whether to move toward or away from things that make us feel good or bad, and it aims to find new ways to help people with anxiety feel better.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11032427 on ClinicalTrials.gov |
What this research studies
This research investigates how specific groups of neurons in the amygdala, a brain region involved in emotional responses, help determine whether we approach or avoid certain stimuli. By using advanced imaging techniques, the researchers will observe the activity of these neurons in response to both positive and negative experiences. The goal is to understand the mechanisms behind avoidance behavior, which is crucial for survival and can impact conditions like anxiety. Patients may benefit from insights that could lead to new treatments for anxiety-related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety or avoidance behaviors.
Not a fit: Patients without anxiety disorders or those not exhibiting avoidance behaviors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for anxiety and other disorders related to avoidance behavior.
How similar studies have performed: Previous research has shown promising results in understanding brain mechanisms related to emotional responses, suggesting potential for success in this area.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PIANTADOSI, SEAN CHRISTOPHER — UNIVERSITY OF WASHINGTON
- Study coordinator: PIANTADOSI, SEAN CHRISTOPHER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.