Understanding how the brain predicts time using neural activity patterns
CRCNS: Multiple clocks for the encoding of time in corticostriatal circuits
This study is looking at how our brains keep track of time and predict events, like when we might find food or face a danger, by examining the activity in a specific brain area called the striatum, and it’s for anyone interested in understanding how our brains work when it comes to timing.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10900572 on NIH RePORTER |
What this research studies
This research investigates how the brain encodes time through neural activity patterns, particularly in the striatum, a key area involved in timing and prediction. By combining experimental techniques and computational models, the study aims to uncover how different brain regions contribute to our ability to anticipate events, such as food availability or potential threats. The researchers will explore the role of neural sequences and how they are influenced by inputs from other brain areas, as well as the function of local circuits in refining these sequences. This work could provide insights into the fundamental mechanisms of temporal processing in the brain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that impair timing and prediction abilities, such as Huntington's disease or other neurological disorders.
Not a fit: Patients without any neurological conditions or those who do not experience difficulties with timing and prediction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of timing and prediction in the brain, potentially leading to new treatments for conditions that affect these cognitive functions.
How similar studies have performed: While the study explores novel aspects of neural timing, similar research has shown promising results in understanding the role of neural sequences in cognitive functions.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Masmanidis, Sotiris — University of California Los Angeles
- Study coordinator: Masmanidis, Sotiris
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.