Understanding how the brain plans complex actions

Identifying the neural correlates of mental simulation in multi-step planning

['FUNDING_R01'] · NEW YORK UNIVERSITY · NIH-11049462

This study is looking at how our brains plan and think about future actions while playing a game called 'Four-in-a-Row,' using special imaging tools to see which parts of the brain are active during decision-making, so we can better understand how we make choices in everyday life.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11049462 on ClinicalTrials.gov

What this research studies

This research investigates the neural mechanisms involved in planning by examining how the brain simulates potential future actions during decision-making. Using a game called 'Four-in-a-Row', the study combines advanced neuroimaging techniques like fMRI and MEG with eye-tracking to analyze brain activity while participants engage in complex planning tasks. The goal is to identify specific brain regions responsible for evaluating potential moves and to understand the timing of these mental simulations. This approach aims to bridge the gap between simplified laboratory tasks and real-life decision-making processes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder or obsessive-compulsive disorder who experience challenges with planning and decision-making.

Not a fit: Patients without planning difficulties or those not diagnosed with autism spectrum disorder or obsessive-compulsive disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for helping individuals with planning difficulties, particularly those with autism spectrum disorder and obsessive-compulsive disorder.

How similar studies have performed: Previous research has shown success in using neuroimaging techniques to study decision-making processes, making this approach both relevant and promising.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.