NIH-funded research NIH-funded research

Understanding how the brain navigates and perceives self-location

Official title: Neural and Computational Architecture for Complex Navigation and Subjective Self-Location

Funded at University of Minnesota · NIH-11081912 · Data updated 2026-11-12

This study looks at how the brain helps us know where we are and how we move around, using experiments with rodents to learn more, which could help people with conditions like autism understand navigation and self-awareness better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startMay 1, 2023
Project endNovember 30, 2027
Funding year2025
Award (this year)$224,101
NIH project number4R00NS128075-03
Project IDNIH-11081912 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research include individuals with autism spectrum disorder who experience challenges with navigation and self-location.

Less likely to help

Patients with conditions unrelated to spatial navigation or self-perception may not receive direct benefits from this research.

What this research studies

This research investigates the neural and computational mechanisms that allow the brain to understand spatial navigation and self-location. By studying rodent neurophysiology, the project aims to uncover how the brain processes information about where we are in space and how we navigate our environment. The research combines behavioral analysis with advanced neurophysiological techniques to explore these complex interactions. Patients may benefit from insights gained about navigation and self-perception, particularly in conditions like autism spectrum disorder.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of spatial navigation and self-awareness, potentially leading to improved interventions for individuals with autism spectrum disorder.

How similar studies have gone: Other research has shown promise in understanding navigation and self-location, particularly in animal models, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Noel, Jean-Paul — University of Minnesota
  • Study coordinator: Noel, Jean-Paul

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.