Understanding how the brain makes flexible decisions in real-world situations

Neural basis of flexible decisions in naturalistic environments

NIH-funded research University of Chicago · NIH-10918212

This study looks at how our brains help us make smart choices in everyday situations, like finding food, and it aims to understand how this process might be different for people with conditions like Alzheimer's disease.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10918212 on NIH RePORTER

What this research studies

This research investigates how the brain processes visual information to make flexible decisions in natural environments, such as when foraging for food. By examining brain activity in areas like the prefrontal cortex, the study aims to uncover how we filter out distractions and adapt our plans based on changing circumstances. Using advanced technologies, the research will explore the neural mechanisms that support these cognitive abilities, which are crucial for navigating complex environments. Patients may benefit from insights into how these processes are affected in conditions like Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related cognitive impairments.

Not a fit: Patients with no cognitive impairments or those with other unrelated neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for cognitive impairments in patients with Alzheimer's disease.

How similar studies have performed: Previous research has shown promising results in understanding cognitive flexibility and decision-making processes, suggesting that this approach could yield valuable insights.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's disease patient
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.