NIH-funded research Career grant

Understanding how the brain makes decisions based on changing information

Official title: Cognitive and Neural Strategies for Latent Feature Inference

Funded at University of Colorado · NIH-10878942 · Data updated 2026-11-12

This study is exploring how our brains learn to make decisions by noticing important details in our surroundings over time, and it's designed for anyone interested in understanding how we adapt our thinking and choices.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado
NIH-funded
Lab location1 site (Boulder, UNITED STATES)
Project startJuly 1, 2023
Project endJune 30, 2025
Funding year2024
Award (this year)$130,354
NIH project number5K99NS127855-02
Project IDNIH-10878942 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals interested in understanding cognitive processes related to decision-making and those experiencing cognitive challenges.

Less likely to help

Patients with severe cognitive impairments that prevent participation in decision-making tasks may not benefit from this research.

What this research studies

This research investigates how humans learn and adapt their decision-making strategies by identifying key features in their environment over different timescales. It focuses on the brain's ability to accumulate evidence for decisions, utilizing both short-term and long-term memory processes, particularly in the hippocampus. By employing computational modeling alongside behavioral and electrophysiological experiments, the study aims to uncover the cognitive strategies and neural mechanisms involved in flexible decision-making. This interdisciplinary approach aligns with the BRAIN initiative's goals to connect behavior with brain function.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of decision-making processes, potentially leading to improved strategies for treating cognitive dysfunctions.

How similar studies have gone: Previous research has shown promising results in understanding decision-making through similar interdisciplinary approaches, indicating potential for success in this area.

Where this research is happening

  • University of Colorado
    Boulder, United States
    Active

Researchers

  • Principal investigator: Eissa, Tahra — University of Colorado
  • Study coordinator: Eissa, Tahra

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.