Understanding how the brain locates sounds
Fast Inhibition in the Sound Localization Pathway
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10809054
This study is exploring how a part of the brain helps us figure out where sounds come from, and it's designed for anyone curious about how our brains process sound.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10809054 on ClinicalTrials.gov |
What this research studies
This research investigates the neural mechanisms involved in sound localization, which is the ability to determine where a sound originates in space. The study focuses on a specific brain region called the medial nucleus of the trapezoid body (MNTB) and its role in processing sound information. Using advanced techniques like optogenetics, researchers will manipulate the activity of MNTB neurons and measure their effects on other brain regions involved in sound localization. This approach aims to fill gaps in our understanding of how the brain interprets sound directionality.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing central hearing loss or difficulties in sound localization.
Not a fit: Patients with normal hearing or those whose hearing loss is not related to sound localization may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals with hearing impairments related to sound localization.
How similar studies have performed: Previous research has shown promising results in understanding auditory processing, but this specific approach using optogenetics in sound localization is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KLUG, ACHIM — UNIVERSITY OF COLORADO DENVER
- Study coordinator: KLUG, ACHIM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.