NIH-funded research R01 grant

Understanding how the brain learns to move and speak

Official title: Fundamental predictive computations in upper-limb and speech adaptation

Funded at Yale University · NIH-11048539 · Data updated 2026-11-12

This study is looking at how our brains learn to move and talk better, which could help people with movement or speech challenges improve their skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startDecember 1, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$440,610
NIH project number1R01NS134754-01A1
Project IDNIH-11048539 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with upper-limb motor impairments or speech disorders who are seeking innovative rehabilitation approaches.

Less likely to help

Patients with stable motor function and no speech difficulties may not receive direct benefits from this research.

What this research studies

This research investigates how the brain adapts movements and speech through a process called motor learning. It focuses on the internal models that predict sensory outcomes and how these models can be influenced by motor plans and sensory feedback, even without actual movement. By using techniques like behavioral studies, electromyography, and functional neuroimaging, the research aims to uncover the neural signals necessary for effective motor learning. This could lead to new insights into rehabilitation strategies for individuals with movement or speech disorders.

Why it matters

Potential benefit: If successful, this research could enhance rehabilitation methods for patients recovering from motor impairments or speech difficulties.

How similar studies have gone: Previous research has shown promising results in understanding motor learning and adaptation, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Mcdougle, Samuel David — Yale University
  • Study coordinator: Mcdougle, Samuel David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.