Understanding how the brain integrates sensory information and internal factors
Feedforward-feedback integration in the posterior parietal cortex
This study is looking at how a part of the brain helps us combine what we see and feel with our memories and goals to make decisions, and it hopes to find ways to help people with mental health issues by understanding how these processes can go wrong.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10842385 on NIH RePORTER |
What this research studies
This research investigates how the brain's posterior parietal cortex (PPC) combines sensory information with internal factors like goals and memories to influence behavior. By using advanced techniques such as optogenetics, researchers aim to uncover the synaptic mechanisms that allow for this integration. The study focuses on understanding how disruptions in these processes may contribute to neuropsychiatric disorders. Patients may benefit from insights gained into how cognitive functions like decision-making and attention are affected by these neural interactions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neuropsychiatric disorders or cognitive impairments.
Not a fit: Patients without cognitive or neuropsychiatric conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neuropsychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding neural integration mechanisms, suggesting that this approach may yield valuable insights.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Lur, Gyorgy — University of California-Irvine
- Study coordinator: Lur, Gyorgy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.