Understanding how the brain helps us bounce back from stress
CRCNS: Multimodal network interactions for internal state dynamics of resiliency
['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11178657
This research aims to uncover how brain networks work together to help individuals cope with stress and maintain well-being.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-11178657 on ClinicalTrials.gov |
What this research studies
We want to understand the complex ways our brains help us be resilient when facing stress, which is vital for everyone's health. While we know stress can be harmful, we don't fully understand how some people naturally recover better than others. This project uses advanced techniques like machine learning and signal processing to look at brain activity, genes, and behaviors in animal models. By combining different types of information, from molecular details to whole-brain connections, we hope to map out the brain circuits that enable resilience. This work could lead to new ways to support mental health and help people better manage life's challenges.
Who could benefit from this research
Good fit: This foundational research uses animal models to understand basic brain mechanisms, so it does not directly involve patient participation at this stage.
Not a fit: Patients will not receive direct clinical benefit from this basic science research, as it focuses on understanding fundamental biological processes in animal models.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of stress resilience, potentially paving the way for new strategies or treatments to help people better cope with stress.
How similar studies have performed: While the detrimental effects of stress are known, this project aims to be the first to provide a comprehensive understanding of the complex interactions underlying resilience, addressing a critical knowledge gap.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, SIHAI DAVE — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: ZHAO, SIHAI DAVE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.