Understanding how the brain helps people use their left hand after right hand nerve injuries

Interhemispheric Communication and Compensation in Peripheral Nerve Injury

['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10993585

This study is looking at how people who have lost function in their right hand can better use their left hand, and it aims to understand how the brain helps with this so that we can create better therapies for those who are working to recover their hand movements.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10993585 on ClinicalTrials.gov

What this research studies

This research investigates how individuals with chronic impairment of their dominant right hand due to peripheral nerve injury can effectively use their non-dominant left hand. It focuses on understanding the brain's interhemispheric communication, which may help in compensating for the loss of function in the right hand. Using advanced neuroimaging techniques, the study aims to identify the neural mechanisms that support left hand usage during tasks that require precision. The ultimate goal is to develop targeted therapies that enhance rehabilitation for patients struggling with motor recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are right-handed individuals aged 21 and older who have experienced chronic impairment of their right hand due to nerve injury.

Not a fit: Patients who have not suffered a nerve injury or those who are left-handed may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation strategies that help patients regain functionality and independence in their daily activities.

How similar studies have performed: While the specific interhemispheric mechanisms in this context are novel, similar neuroimaging approaches have shown promise in understanding brain compensation strategies in other neurological conditions.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.