Understanding how the brain encodes rewards in memory and navigation.
Precise neuromodulation for encoding reward in the hippocampus
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10895448
This study is looking at how the brain's reward system works in a part of the brain called the hippocampus, which helps us remember and find our way around, to see how certain chemicals affect our memories and choices, especially in relation to conditions like addiction.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10895448 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which the brain encodes reward information in the hippocampus, a critical area for memory and navigation. Using advanced imaging techniques, the study will observe how dopamine and norepinephrine influence the activity of place cells—neurons that help map our environment—when animals navigate through virtual spaces. By examining these interactions, the research aims to uncover how rewards affect memory and decision-making processes. This could lead to insights into conditions like addiction and other behavioral disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with conditions related to reward processing, such as addiction or memory impairments.
Not a fit: Patients who do not have issues related to reward processing or memory may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of reward processing in the brain, potentially leading to better treatments for addiction and memory-related disorders.
How similar studies have performed: Other research has shown promising results in understanding reward mechanisms in the brain, suggesting that this approach could yield valuable insights.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GIOCOMO, LISA — STANFORD UNIVERSITY
- Study coordinator: GIOCOMO, LISA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.