Understanding how the brain encodes information for decision-making

P2: Geometry of Neural Representations and Dynamics

['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-10900683

This study looks at how our brains represent information when we make decisions, focusing on the activity of certain brain cells, and the findings could help improve treatments for memory and thinking problems.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPRINCETON UNIVERSITY (nih funded)
Locations1 site (Princeton, UNITED STATES)
Trial IDNIH-10900683 on ClinicalTrials.gov

What this research studies

This research investigates the geometric properties of neural coding in the brain, specifically focusing on how information is represented during decision-making tasks. By studying the activity of neurons in the dorsal hippocampus and other brain regions, the researchers aim to model how different cognitive variables are encoded geometrically. This involves measuring neural activity patterns and comparing them to existing statistical models to better understand the underlying mechanisms of working memory and decision-making. Patients may benefit from insights gained about brain function that could inform future treatments for cognitive disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with cognitive impairments or disorders affecting decision-making and memory.

Not a fit: Patients with no cognitive impairments or those not experiencing decision-making difficulties may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for cognitive disorders related to decision-making and memory.

How similar studies have performed: Other research has shown success in understanding neural coding and decision-making, but this specific geometric approach is relatively novel.

Where this research is happening

Princeton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.