NIH-funded research NIH-funded research

Understanding how the brain encodes information for decision-making

Official title: P2: Geometry of Neural Representations and Dynamics

Funded at Princeton University · NIH-10900683 · Data updated 2026-11-12

This study looks at how our brains represent information when we make decisions, focusing on the activity of certain brain cells, and the findings could help improve treatments for memory and thinking problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPrinceton University
NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project startAugust 8, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$324,363
NIH project number5U19NS132720-02
Project IDNIH-10900683 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals with cognitive impairments or disorders affecting decision-making and memory.

Less likely to help

Patients with no cognitive impairments or those not experiencing decision-making difficulties may not receive direct benefits from this research.

What this research studies

This research investigates the geometric properties of neural coding in the brain, specifically focusing on how information is represented during decision-making tasks. By studying the activity of neurons in the dorsal hippocampus and other brain regions, the researchers aim to model how different cognitive variables are encoded geometrically. This involves measuring neural activity patterns and comparing them to existing statistical models to better understand the underlying mechanisms of working memory and decision-making. Patients may benefit from insights gained about brain function that could inform future treatments for cognitive disorders.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for cognitive disorders related to decision-making and memory.

How similar studies have gone: Other research has shown success in understanding neural coding and decision-making, but this specific geometric approach is relatively novel.

Where this research is happening

  • Princeton University
    Princeton, United States
    Active

Researchers

  • Principal investigator: Brody, Carlos D — Princeton University
  • Study coordinator: Brody, Carlos D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.