Understanding how the brain develops and connects neurons over time
A Connectomic Analysis of a Developing Brain Undergoing Neurogenesis
['FUNDING_R01'] · UNIVERSITY OF MASSACHUSETTS AMHERST · NIH-10909319
This study is looking at how the brain grows and changes as new brain cells are made, using a special sea creature called Berghia stephanieae, to help us learn more about how brain networks develop, which could be useful for understanding brain issues that happen when development goes wrong.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MASSACHUSETTS AMHERST (nih funded) |
| Locations | 1 site (HADLEY, UNITED STATES) |
| Trial ID | NIH-10909319 on ClinicalTrials.gov |
What this research studies
This research investigates the development of neural circuits in the brain as new neurons are formed and integrated into existing networks. Using a unique animal model, the mollusc Berghia stephanieae, researchers will create detailed wiring diagrams of the brain at various stages of development. By tracking changes in specific neurons and their connections, the study aims to uncover fundamental insights into how brain networks grow and adapt, which could help in understanding neurological conditions linked to improper brain development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who may be affected by neurological conditions or are interested in brain development.
Not a fit: Patients with fully developed brains or those over 21 years old may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of neurological conditions related to brain development.
How similar studies have performed: While this approach is novel in its specific application to the mollusc model, similar studies in other species have shown promise in understanding brain development.
Where this research is happening
HADLEY, UNITED STATES
- UNIVERSITY OF MASSACHUSETTS AMHERST — HADLEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KATZ, PAUL S — UNIVERSITY OF MASSACHUSETTS AMHERST
- Study coordinator: KATZ, PAUL S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.