Understanding how the brain detects and processes pain.
Neural Coding and Control of Pain Detection in Somatosensory Cortex
['FUNDING_R01'] · CLEVELAND CLINIC LERNER COM-CWRU · NIH-11056445
This study looks at how the brain senses and processes pain, especially in people who have ongoing pain, by using special techniques on mice to learn more about how brain activity relates to pain, with the hope of finding better ways to manage pain in the future.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEVELAND CLINIC LERNER COM-CWRU (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11056445 on ClinicalTrials.gov |
What this research studies
This research investigates the brain's somatosensory cortex to understand how it detects and processes pain, particularly in individuals with chronic pain conditions. The study employs advanced techniques, including electrophysiological recordings and optogenetic interventions, to analyze neural activity patterns in mice. By examining the relationship between brain oscillations and pain responses, the research aims to uncover the underlying mechanisms of pain perception, which could lead to improved pain management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic pain conditions, as well as healthy participants for comparative analysis.
Not a fit: Patients with acute pain or those not experiencing chronic pain conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic and therapeutic approaches for managing pain more effectively.
How similar studies have performed: Previous research has shown promise in understanding pain mechanisms through similar electrophysiological approaches, indicating potential for success in this area.
Where this research is happening
CLEVELAND, UNITED STATES
- CLEVELAND CLINIC LERNER COM-CWRU — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SAAB, CARL Y — CLEVELAND CLINIC LERNER COM-CWRU
- Study coordinator: SAAB, CARL Y
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.