Understanding how the brain decodes meanings in speech after a stroke

Decoding mental concept identities using electrocorticography

NIH-funded research Medical College of Wisconsin · NIH-11072058

This study is working on a new technology that could help people with aphasia, which makes it hard to speak after a stroke, by using brain signals to improve communication.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-11072058 on NIH RePORTER

What this research studies

This research focuses on developing a brain-computer interface (BCI) that can help individuals with aphasia, a common condition following a stroke that affects speech. The project aims to decode brain activity related to semantic concepts using advanced machine learning techniques. Initially, the researchers will gather data from patients without language deficits during awake brain surgeries, using high-density electrocorticography (ECoG) to record brain activity. The goal is to create a model that can later be applied to individuals with severe aphasia, using non-invasive methods to assist in their communication.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are suffering from severe aphasia.

Not a fit: Patients who do not have aphasia or have only mild language deficits may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new treatment option for patients with severe aphasia, potentially improving their ability to communicate.

How similar studies have performed: While the approach of using brain-computer interfaces is gaining traction, this specific application for decoding semantic concepts in aphasia is relatively novel and has not been extensively tested.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.