NIH-funded research Career grant

Understanding how the brain creates new behaviors

Official title: Investigating Symbolic Computation in the Brain: Neural Mechanisms of Compositionality

Funded at Rockefeller University · NIH-10875523 · Data updated 2026-11-12

This study is exploring how our brains help us come up with new and flexible actions, using a fun drawing task with monkeys to see how different parts of the brain work together to create these behaviors.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionRockefeller University
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 16, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$134,271
NIH project number5K99NS131585-02
Project IDNIH-10875523 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals with cognitive disorders or those interested in the mechanisms of learning and behavior.

Less likely to help

Patients with severe neurological impairments that prevent participation in cognitive tasks may not benefit from this research.

What this research studies

This research investigates the neural mechanisms behind how animals, including humans, generate new and flexible behaviors. By using a unique drawing task with macaques, the study aims to uncover how the brain combines learned elements to create novel actions. The approach involves large-scale recordings from multiple areas of the frontal cortex to understand their roles in cognitive processes. This innovative methodology seeks to fill a gap in our understanding of compositional planning in the brain.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cognitive disorders and lead to new therapeutic strategies.

How similar studies have gone: While the specific approach of this research is novel, similar studies have shown promise in understanding cognitive functions through innovative behavioral tasks.

Where this research is happening

  • Rockefeller University
    New York, United States
    Active

Researchers

  • Principal investigator: Tian, Lucas Y. — Rockefeller University
  • Study coordinator: Tian, Lucas Y.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.