NIH-funded research NIH-funded research

Understanding how the brain coordinates facial movements

Official title: Administrative Core

Funded at University of California, San Diego · NIH-10930312 · Data updated 2026-11-12

This study is looking at how the brain controls facial movements, using special tools to see what happens in the brain, and it aims to help people with conditions that affect their ability to move their face.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startAugust 15, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$289,302
NIH project number1U19NS137920-01
Project IDNIH-10930312 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit would include individuals with conditions that impact facial movement or coordination.

Less likely to help

Patients without any neurological or orofacial disorders may not receive direct benefits from this research.

What this research studies

This research focuses on the neuronal mechanisms that control coordinated orofacial behavior, utilizing advanced techniques such as 2-photon microscopy and in vivo electrophysiology. The project is organized into multiple studies across various sites, leveraging expertise in genetic manipulation and automated image recognition to analyze brain connectivity. Patients may benefit from insights gained about brain function related to facial movements, which could inform treatments for conditions affecting these behaviors.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for disorders affecting facial coordination.

How similar studies have gone: Other research utilizing advanced imaging and electrophysiological techniques has shown promise in understanding brain functions, suggesting potential success for this approach.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Kleinfeld, David — University of California, San Diego
  • Study coordinator: Kleinfeld, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.