Understanding how the brain coordinates complex movements and actions
Neural population geometry and dynamics underlying multi-step cognitive-motor sequencing
['FUNDING_CAREER'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11033282
This study looks at how different parts of the brain work together to help us plan and carry out movements we need for everyday tasks, using Rhesus macaques to learn more about how these brain areas communicate, which could help us understand conditions like Parkinson's disease better.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11033282 on ClinicalTrials.gov |
What this research studies
This research investigates how different areas of the brain work together to plan and execute complex sequences of movements, which are essential for daily activities. By studying Rhesus macaques, the researchers will observe how these brain regions communicate and function during multi-step tasks. They will use advanced techniques to measure brain activity and analyze how information is processed to generate movement sequences. This approach aims to uncover the underlying neural mechanisms that can be affected by disorders like Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with movement disorders, such as Parkinson's disease, who experience difficulties in planning and executing movements.
Not a fit: Patients without any cognitive or motor impairments may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for patients with movement disorders, enhancing their ability to perform daily activities.
How similar studies have performed: Previous research has shown success in understanding motor sequencing through similar approaches, indicating a promising avenue for further exploration.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VYAS, SAURABH — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: VYAS, SAURABH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.