Understanding how the brain coordinates complex movements and actions
Official title: Neural population geometry and dynamics underlying multi-step cognitive-motor sequencing
Funded at Columbia University Health Sciences · NIH-11033282 · Data updated 2026-11-12
This study looks at how different parts of the brain work together to help us plan and carry out movements we need for everyday tasks, using Rhesus macaques to learn more about how these brain areas communicate, which could help us understand conditions like Parkinson's disease better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $126,333 |
| NIH project number | 1K99NS140554-01 |
| Project ID | NIH-11033282 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with movement disorders, such as Parkinson's disease, who experience difficulties in planning and executing movements.
✕Less likely to help
Patients without any cognitive or motor impairments may not receive direct benefits from this research.
What this research studies
This research investigates how different areas of the brain work together to plan and execute complex sequences of movements, which are essential for daily activities. By studying Rhesus macaques, the researchers will observe how these brain regions communicate and function during multi-step tasks. They will use advanced techniques to measure brain activity and analyze how information is processed to generate movement sequences. This approach aims to uncover the underlying neural mechanisms that can be affected by disorders like Parkinson's disease.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for patients with movement disorders, enhancing their ability to perform daily activities.
How similar studies have gone: Previous research has shown success in understanding motor sequencing through similar approaches, indicating a promising avenue for further exploration.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Vyas, Saurabh — Columbia University Health Sciences
- Study coordinator: Vyas, Saurabh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.