Understanding how the brain controls walking movements
Investigating Descending Control of Walking
This study is looking at how the brain controls walking and aims to understand the problems that can cause movement issues in conditions like ALS and Parkinson's disease, with the hope of improving treatments and creating better prosthetics and robots that move like we do.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10708171 on NIH RePORTER |
What this research studies
This research investigates the brain circuits responsible for controlling motor output, specifically focusing on walking behavior. By examining how individual neurons encode features of movement, the study aims to uncover the mechanisms behind movement disorders like amyotrophic lateral sclerosis (ALS) and Parkinson's disease. The research will involve advanced techniques in connectomics and modeling, conducted in a leading neurobiology lab at Harvard Medical School. The ultimate goal is to enhance our understanding of motor control and inform the development of prosthetics and robotics that mimic natural movement.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with movement disorders such as amyotrophic lateral sclerosis or Parkinson's disease.
Not a fit: Patients with movement disorders not related to the brain's motor control circuits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and technologies for individuals suffering from movement disorders.
How similar studies have performed: Previous research has shown promise in understanding motor control through similar approaches, indicating potential for significant advancements.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Yang, Helen Horan — Harvard Medical School
- Study coordinator: Yang, Helen Horan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.