NIH-funded research Career grant

Understanding how the brain controls stopping speech

Official title: Neural mechanisms for stopping ongoing speech production

Funded at University of California, San Francisco · NIH-10738305 · Data updated 2026-11-12

This study is looking at how our brains help us control when to stop talking during conversations, which could help us understand speech issues like stuttering and aphasia better.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startDecember 1, 2022
Project endJune 30, 2025
Funding year2024
Award (this year)$122,904
NIH project number5K99DC020235-02
Project IDNIH-10738305 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing speech production difficulties, such as those with aphasia or stuttering.

Less likely to help

Patients without any speech or communication disorders may not receive direct benefits from this research.

What this research studies

This research investigates the neural mechanisms that allow individuals to precisely control the timing of their speech during conversations, particularly focusing on how to quickly stop speaking before finishing an utterance. By examining the neural circuits involved in speech production, especially in areas of the brain like the sensorimotor and premotor cortices, the study aims to uncover how these circuits respond to cues that signal a stop in speech. The findings could provide insights into normal speech production and the underlying causes of communication disorders such as stuttering and aphasia.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for speech and communication disorders.

How similar studies have gone: Previous research has shown success in understanding neural mechanisms related to speech production, but this specific focus on stopping speech is relatively novel.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Zhao, Lingyun — University of California, San Francisco
  • Study coordinator: Zhao, Lingyun

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.