Understanding how the brain controls movement and force during object manipulation

Motor cortical signaling of impedance during manipulation

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10832972

This study looks at how the brain helps us move and apply force when we use tools, and it's designed for anyone interested in understanding how we control our movements better, which could help improve rehabilitation methods.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10832972 on ClinicalTrials.gov

What this research studies

This research investigates how the motor cortex of the brain encodes both movement and force when interacting with objects. By studying primates, the researchers aim to develop new models that explain how the brain coordinates these two aspects, known as impedance. The project involves recording neural activity while the subjects perform tasks with real and virtual tools, allowing for a detailed analysis of how the brain signals force and motion together. The findings could enhance our understanding of motor control and rehabilitation strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with motor impairments or those undergoing rehabilitation for conditions affecting their movement.

Not a fit: Patients with neurological conditions unrelated to motor control or those who do not require rehabilitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation therapies for patients with motor control issues.

How similar studies have performed: While there has been extensive research on movement velocity, this approach to understanding impedance in motor control is relatively novel and has not been extensively tested.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.